Xeljanz (tofacitinib citrate), an oral DMARD (disease-modifying anti-rheumatic drug), was approved by the U.S. Food and Drug Administration (FDA) on November 6, 2012. The drug is intended for the treatment of adults with moderately to severely active rheumatoid arthritis, a disease of the immune system which damages and inflames the joints. This medicine is also used to treat a certain bowel disease (ulcerative colitis) and psoriatic arthritis. Xeljanz can be used as monotherapy (alone) or combined with methotrexate or other non-biologic DMARDs.
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